We have visually separated the litter box (a covered Buddhabox) from the rest of the room with cardboard boxes barricading two sides of the litter box. The litter box sits on the floor against a wall, and only the opening doesn't have a barricade.
We have also visually separated the cats' water and food dishes by putting the dishes on the base shelf of an old TV stand. The base shelf is 4-5" off the ground, and it provides an ergonomic feeding position for the cats.
1st time mom to Maya the Mighty b. 3/2003