I'd do hotel. I'd trust hotel cleaning protocols better than AirBnB. Either way you are probably wiping surfaces down yourself. I'd chose a hotel or motel with either an outdoor entrance to the room (like motel) or a hotel with just a few floors to shorten an elevator ride or be able to take stairs. I'd also request a room that was not occupied that day, if possible.
Mom to two amazing DDs ('07 & '09) and a fur baby.
Gluten free since Nov '11 after non-celiac gluten sensitive diagnosis. Have had great improvement or total elimination of: migraines, bloating/distention, heartburn, cystic acne, canker sores, bleeding gums, eczema on elbows, dry skin and scalp, muscle cramps, PMS, hair loss, heart palpitations, fatigue. I'm amazed.