I read a lot of design blogs and magazines and can’t say I’ve ever seen a bedroom with 2 runners, it seems to me it would make the room look choppy and “off”. My vote is for 1 large rug (and definitely a rug vs no rug). Your room is very neutral as it is, so I think you need a large patterned rug to ground it. I really like both your 1st and 2nd pick rugs.