I think it boils down to family preferences. We currently have a washer/dryer on our main floor as well as a laundry room between our kids' bedrooms on our second floor. I far prefer the upstairs washer and dryer for the simple fact that I hate carrying loads of clothes up or down the stairs. In our last house, the washer/dryer was off the kitchen. But every house before that had the washer/dryer on the floor below our bedrooms and closets which meant lugging around loads of clothes. I absolutely hate that. I could see missing the space to dry things out flat but it wouldn't change my opinion. I would happily fold clothes on my bed if it meant keeping the w/d upstairs. All of my kids are heavy sleepers so I can run the washer dryer in the early morning or evening without any complaints. Mainly I run it during the day because i have that luxury as a sahm. Those are all things to think about.
If we didn't have an outdoor pool and use an obscene amount of pool towels, the main floor washer/dryer would probably only be used to occasionally wash basement guest room linens as well as kitchen towels and winter coats. Now that my kids are washing their own laundry, they are the only ones who really use the main floor w/d.
" I object to violence because when it appears to do good, the good is only temporary; the evil it does is permanent." Mahatma Gandhi
"This is the ultimate weakness of violence: It multiplies evil and violence in the universe. It doesn't solve any problems." Martin Luther King, Jr.